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Image Search Results
Journal: Development (Cambridge, England)
Article Title: Feedback between tissue packing and neurogenesis in the zebrafish neural tube
doi: 10.1242/dev.157040
Figure Lengend Snippet: Notch activity as a potential readout of nuclear position. (A) nort:d2GFP expression reports Notch activity in the neural tube. Arrowhead indicates GFP-negative basally localized neurons. Scale bar: 10 µm. (B) Notch activity (green) is significantly inhibited in progenitors that are adjacent (and basal) to an arrested mitotic cell (magenta) (P<0.01, n=15 for control, n=12 for dnPLK1). (C) Inhibition of Notch signaling (via microinjection of hsp:dnMAML1-P2A-h2bCherry2) promotes differentiation compared with a control injection (hsp:h2bCherry2) (P<0.001 for n=11). Scale bar: 10 µm.
Article Snippet: The hsp:mTagBFP2-dnPLK1-2A-p50 was similarly made, but with two extra pieces: the
Techniques: Activity Assay, Expressing, Control, Inhibition, Microinjection, Injection